Brella® SweatControl Patch
Brellalogo 1681230072420 HR 1In April 2023, the U.S. FDA cleared for use the Brella® SweatControl Patch for the treatment of excessive underarm sweating (primary axillary hyperhidrosis) in adults (use for anyone under 18 would be off-label and up to the clinician's discretion). Brella was created by Candesant Biomedical, headquartered in Nashville, TN.
Important update as of June 2025: The company behind Brella, Candesant Biomedical, is currently in the process of being sold. As a result, there are no Brella sales representatives available at this time, and access to the treatment is currently limited. We will continue to share updates as soon as more information becomes available.
The Brella patch is a prescription product designed and cleared to be applied at a healthcare provider’s office or clinic for approximately 3 minutes (no more than 3 minutes but, depending on the patient, treatment could take less than 3 minutes) and works via a method called targeted alkali thermolysis (TAT). Depending on regulations in different U.S. states, Brella treatment may be provided by a physician, physician assistant, nurse practitioner or nurse.
Brella is oval shaped to fit the underarm and contains pure metallic sodium with zero aluminum. The patch itself is, according to Candesant, a "very standard, medical-grade adhesive patch."
Learn more! Watch our new "Ask Me Anything" video all about Brella with special guest Niquette Hunt, Candesant CEO.
The TAT technology behind Brella is based on the principle that heat is generated when sodium meets water. The result is that
when the Brella sodium patch is applied to the underarm, there’s an interaction between the water in sweat and the sodium in the patch that generates a targeted amount of heat, causing microthermal injury to the sweat glands that inactivates those glands for a period of time. The process is non-invasive and does not involve needles. No pain control or anesthesia is required prior, during, or after Brella.
About 48 or more hours before Brella treatment, patients should shave their underarms. In the office, prior to patch application, providers will ensure skin is dry. Once applied, the patch works through the interaction of its sodium with the water in sweat that begins to come out of the sweat glands. To stimulate sweating, if needed, clinicians are provided with a number of tips from the makers of Brella. Patients report that, during Brella treatment, they feel: "tingling," "prickles" or "pins and needles." The entire in-office visit to receive Brella treatment for both underarms is expected to take about 20 minutes. Results usually become apparent 3 to 5 days after treatment and last 2 to 4 months.
The FDA’s clearance of Brella was based on data from a randomized, double-blind, multicenter study that included 110 adult patients with primary axillary (underarm) hyperhidrosis. Patients had baseline Hyperhidrosis Disease Severity Scale (HDSS) scores of 3 or 4, which showed that excessive sweating frequently or always interfered with their daily lives. Patients in the study then received treatment with Brella or with a sham (fake or placebo) patch for up to 3 minutes on each underarm. Afterwards, patients were evaluated weekly for 12 weeks (~3 months), and again at 24 weeks (~6 months) post-treatment.
Results were presented in 2023 at the American Academy of Dermatology Annual Meeting and showed that 64% of patients treated with the patch achieved Hyperhidrosis Disease Severity Scale improvement as compared with 44% with placebo. Measured sweat production decreased by more than 50% for most (60%) of treated patients.
There were no reported serious or severe adverse events (side effects) among the study participants. Eighty percent of people in the study had no side effects at all and those who did experienced slight redness or slight swelling that resolved within two weeks or less. There were no lasting side effects and any side effects were transient and went away on their own.
The Brella study results “are exciting,” says Dr. David Pariser, professor at the Eastern Virginia Medical School Department of Dermatology and founding member of the International Hyperhidrosis Society (IHhS) “because they demonstrate consistent, statistically significant, and clinically meaningful improvements across the measured hyperhidrosis parameters.”
Brella was available in certain areas of the U.S. beginning in mid 2023 through a “Brella Early Experience Program.” The initial healthcare offices able to provide Brella were dermatology and plastic surgery practices with prior experience treating patients with excessive sweating.
Candesant created a MyBrella.com clinician finder and mailing list for updates on Brella's rollout, but given the company is being sold, it is unclear if and when these online tools will be updated and monitored.
How much does Brella cost? Hunt said she expected doctors wouldcharge about the same for one session with the patch as they would for a high-end, in-office facial or chemical peel. The average cost of a chemical peel in the US, according to the American Society of Plastic Surgeons, is about $500. But, there can be additional office visit costs, etc. IHhS spoke with one aesthetic practice in Texas that indicated they would provide Brella for a total cost of about $350. This is, of course, just one example and not indicative of widespread pricing.
Can Brella be used on other sweaty body areas beyond the underarms? Some experts hint there may be off-label potential for the use of Brella on different body parts.
Bron:
https://www.sweathelp.org/hyperhidrosis ... rella.html
Ik kan alleen nergens achterhalen hoeveel patches je krijgt voor 350 dollar en het werkt maar 3 maanden en zo'n 60 procent zweetafname. Aangezien het bedrijf achter Brella verkocht is vraag ik me af of dit ooit naar Europa komt eerlijk gezegd.
